Dynamically changing font size of UILabel

I currently have a UILabel:

factLabel = [[UILabel alloc] initWithFrame:CGRectMake(20, 100, 280, 100)];
factLabel.text = @"some text some text some text some text";
factLabel.backgroundColor = [UIColor clearColor];
factLabel.lineBreakMode = UILineBreakModeWordWrap;
factLabel.numberOfLines = 10;
[self.view addSubview:factLabel];

Throughout the life of my iOS application, factLabel gets a bunch of different values. Some with multiple sentences, others with just 5 or 6 words.

How can I set up the UILabel so that the font size changes so that the text always fits in the bounds I defined?