Android – set TextView TextStyle programmatically?

Is there a way to set the textStyle attribute of a TextView programmatically? There doesn’t appear to be a setTextStyle() method.

To be clear, I am not talking about View / Widget styles! I am talking about the following:

<TextView
  android:id="@+id/my_text"
  android:layout_width="fill_parent"
  android:layout_height="wrap_content"
  android:text="Hello World"
  android:textStyle="bold" />