How to select all columns, except one column in pandas?

I have a dataframe look like this:

import pandas
import numpy as np
df = DataFrame(np.random.rand(4,4), columns = list('abcd'))
df
      a         b         c         d
0  0.418762  0.042369  0.869203  0.972314
1  0.991058  0.510228  0.594784  0.534366
2  0.407472  0.259811  0.396664  0.894202
3  0.726168  0.139531  0.324932  0.906575

How I can get all columns except column b?

When the columns are not a MultiIndex, df.columns is just an array of column names so you can do:

df.loc[:, df.columns != 'b']

          a         c         d
0  0.561196  0.013768  0.772827
1  0.882641  0.615396  0.075381
2  0.368824  0.651378  0.397203
3  0.788730  0.568099  0.869127