Cannot obtain value of local or argument as it is not available at this instruction pointer, possibly because it has been optimized away

Visual Studio 2010 kills (there is no other word) data in one of the arguments of the function in the unsafe block.
What could cause this error? The following message shows by the debugger.

Cannot obtain value of local or argument as it is not available at this instruction pointer, possibly because it has been optimized away.

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